Understanding COVID-19 News Coverage using Medical NLP

Being a global pandemic, the COVID-19 outbreak received global media attention. In this study, we analyze news publications from CNN and The Guardian - two of the world's most influential media organizations. The dataset includes more than 36,000 articles, analyzed using the clinical and biomedical Natural Language Processing (NLP) models from the Spark NLP for Healthcare library, which enables a deeper analysis of medical concepts than previously achieved. The analysis covers key entities and phrases, observed biases, and change over time in news coverage by correlating mined medical symptoms, procedures, drugs, and guidance with commonly mentioned demographic and occupational groups. Another analysis is of extracted Adverse Drug Events about drug and vaccine manufacturers, which when reported by major news outlets has an impact on vaccine hesitancy. © 2021 Copyright for this paper by its authors

Hydroxyurea-induced genital ulcers and erosions: Two case reports.

Hydroxyurea is a chemotherapeutic agent used for myeloproliferative disorders and sickle cell anemia that is well known to cause painful mucocutaneous ulcers, typically involving the legs or mouth. However, genital ulcerations due to hydroxyurea therapy are a rare, and likely underrecognized, adverse effect with only a few cases reported in the literature to date. Ulcers of the lower legs caused by hydroxyurea are associated with a diagnostic delay, and this is likely exacerbated in cases of genital ulceration due to a lack of awareness. Herein we present two cases of painful genital ulceration in patients on hydroxyurea therapy. In the first Case, an 87 year-old male with polycythemia vera developed an ulcer on the scrotum, which was assessed initially through virtual visits during the COVID-19 pandemic, and was refractory to topical and oral antibiotic treatments. The second case was a 79 year-old male with essential thrombocythemia and a history of persistent leg ulcers who developed erosions of the glans penis. Both patients experienced complete resolution within weeks of discontinuing hydroxyurea therapy. In conclusion, genital ulcers and erosions induced by hydroxyrea may be underrecognized in clinical practice, but if identified, withdrawal of hydroxyurea leads to quick resolution of these lesions and the associated pain.